Preferred Label : Diffuse Large B-Cell Lymphoma;
NCIt synonyms : DLBCL;
NCIt related terms : Diffuse Large B-Cell Lymphoma (DLBCL); Diffuse large B-cell lymphoma, unspecified site; Non-follicular (diffuse) lymphoma, unspecified, unspecified site;
NCIt definition : A non-Hodgkin lymphoma characterized by a diffuse proliferation of predominantly large
neoplastic B lymphocytes. It is the most frequently seen type of non-Hodgkin lymphoma,
representing 30%-40% of the cases. Morphologic variants include centroblastic lymphoma,
immunoblastic lymphoma, and anaplastic lymphoma. Subtypes/entities include T-cell/histiocyte
rich large B-cell lymphoma, primary diffuse large B-cell lymphoma of the central nervous
system, plasmablastic lymphoma, primary cutaneous diffuse large B-cell lymphoma, leg
type, and ALK-positive large B-cell lymphoma.;
Alternative definition : NCI-GLOSS: A type of B-cell non-Hodgkin lymphoma (cancer of the immune system) that
is usually aggressive (fast-growing). It is the most common type of non-Hodgkin lymphoma,
and is marked by rapidly growing tumors in the lymph nodes, spleen, liver, bone marrow,
or other organs. Other symptoms include fever, night sweats, and weight loss. There
are several subtypes of diffuse large B-cell lymphoma.;
Neoplastic status : Malignant;
ICD-O code : 9680/3;
Codes from synonyms : 10012820; CDR0000428286; C83.30; C83.90;
Origin ID : C8851;
UMLS CUI : C0079744;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Disease excludes abnormal cell
- Disease excludes normal cell origin
- Has associated anatomic sites
- Manual BTNT mappings - CISMeF
- Semantic type(s)
- UMLS correspondences (same concept)
- associated_with_malfunction_of_gene_product
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_associated_disease
- disease_has_associated_gene
- disease_has_finding
- disease_has_molecular_abnormality
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_may_have_molecular_abnormality
- human_disease_maps_to_eo_disease
