Preferred Label : Isoprostane;
NCIt synonyms : Isoprostanes;
NCIt definition : A group of compounds similar to prostaglandins with immunomodulating activity. Isoprostanes
are formed through free radical catalyzing non-enzymatic reactions involving peroxidation
of essential fatty acids, mainly arachidonic acid or any other fatty acid with 3 or
more double bonds. Isoprostanes are abundant in tissues and fluids and their concentration
is dependent on the amount of oxidative stress and may be upregulated in certain diseases
such as cancer, cardiovascular and neurological disorders.;
Origin ID : C87059;
UMLS CUI : C0949860;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
