MeSH definition : A series of prostaglandin-like compounds that are produced by the attack of free-radical
species on unsaturated fatty acids, especially ARACHIDONIC ACID, of cellular MEMBRANES.
Once cleaved from the lipid membrane by the action of phospholipases they can circulate
into various bodily fluids and eventually be excreted. Although these compounds resemble
enzymatically synthesized prostaglandins their stereoisometric arrangement is usually
different than the naturally occurring compounds.;
MeSH synonym : isoprostane;
Wikipedia link : https://en.wikipedia.org/wiki/Isoprostane;
A series of prostaglandin-like compounds that are produced by the attack of free-radical
species on unsaturated fatty acids, especially ARACHIDONIC ACID, of cellular MEMBRANES.
Once cleaved from the lipid membrane by the action of phospholipases they can circulate
into various bodily fluids and eventually be excreted. Although these compounds resemble
enzymatically synthesized prostaglandins their stereoisometric arrangement is usually
different than the naturally occurring compounds.