Selenium - CISMeF

Preferred Label : Selenium;

NCIt synonyms : Se;

NCIt definition : A nonmetallic chemical element found in trace amounts in human body. Selenium primarily occurs in vivo as selenocompounds, mostly selenoproteins such as glutathione peroxidase and thioredoxin reductase (enzymes responsible for detoxification). Alone or in combination with Vitamin E, selenocompounds act as antioxidants. These agents scavenge free radicals; prevent blood clots by inhibiting platelet aggregation; strengthen the immune system; and have been shown, in some instances, to inhibit chromosomal damage and mutations. Exhibiting chemopreventive activity, selenocompounds also inhibit the induction of protein kinase C.;

Alternative definition : NCI-GLOSS: A mineral that is needed by the body to stay healthy. It is being studied in the prevention and treatment of some types of cancer. Selenium is a type of antioxidant.;

UNII : H6241UJ22B;

InChIKey : BUGBHKTXTAQXES-UHFFFAOYSA-N;

CAS number : 7782-49-2;

Chemical formula : Se;

ChEBI ID : CHEBI:27568; CHEBI:36904;

Codes from synonyms : CDR0000045113; 00930;

Details

Origin ID

C825;

UMLS CUI

C0036581;

Automatic exact mappings (from CISMeF team)
- Fucosyltransferase 2 [OMIM gene]
- Product containing selenium (medicinal product) [SNOMED CT concept]
- Secondary diagnosis [LOINC component]
- Secondary diagnosis (contextual qualifier) (qualifier value) [SNOMED CT concept]
- Selenium low [MedDRA LLT]
- minerals [MedlinePlus Topic]
- septum of telencephalon [UBERON concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Element, Ion, or Isotope [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing selenium (medicinal product) [SNOMED CT concept]
- Selenium [LOINC component]
- Selenium (substance) [SNOMED CT concept]
- selenium [Radlex concept]
- selenium [MeSH concept]
- selenium [MeSH Descriptor]
- selenium, nos [SNOMED Notion]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Ascorbic acid/Selenium [NCIt concept]
- Ascorbic acid/Selenium/Vitamin E [NCIt concept]
- Celecoxib/Selenium [NCIt concept]
- Selenium/Soy Protein Isolate/Vitamin E [NCIt concept]
- Selenium/vitamin E [NCIt concept]

Keyword's position in hierarchy(ies) :

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