Fucosyltransferase 2

Preferred Label : Fucosyltransferase 2;

Symbol : FUT2;

CISMeF acronym : FUT2;

Type : Gene;

Alternative titles and symbols : Secretor factor; Se; SEC2;

Description : The classic human secretor locus (Se) FUT2 encodes alpha-(1,2)fucosyltransferase, which regulates expression of the Lewis ABO(H) histo-blood group antigens on the surface of epithelial cells and in body fluids and determines the secretion status of the ABO antigens (see 110300). Secretor status of this polymorphic protein was used by Mohr (1951) to provide the first autosomal linkage in humans between secretor factor and the Lutheran blood group (see 111200) (summary by Hazra et al., 2008). The secretor factor (Se) might be considered either a physiologic trait or an honorary blood group (VAM). The individual who is a so-called secretor has demonstrable ABH blood group antigen in the saliva and other body fluids; the nonsecretor does not. Secretor is dominant.;

Ensembl ID : ENSG00000176920;

Prefixed ID : *182100;

Details

Origin ID

182100;

UMLS CUI

C1414863;

Automatic exact mappings (from CISMeF team)
- Galactoside 2-alpha-L-fucosyltransferase [MeSH Descriptor]
- Secondary diagnosis [LOINC component]
- Secondary diagnosis (contextual qualifier) (qualifier value) [SNOMED CT concept]
- Selenium [NCIt concept]
- Sleep Efficiency [NCIt concept]
- Standard Error [NCIt concept]
- Subject Element Domain [NCIt concept]
- Sweden [NCIt concept]
- fucosyltransferase 2 [HGNC gene]
- galactoside 2-alpha-L-fucosyltransferase [MeSH Supplementary Concept]
- selenium [Artificial nutrition thesaurus concept]
- septum of telencephalon [UBERON concept]
HGNC gene
- fucosyltransferase 2 [HGNC gene]
Phenotypes related
- Bombay phenotype [OMIM Phenotype]
- Vitamin b12 plasma level quantitative trait locus 1 [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- fucosyltransferase 2 [HGNC gene]

Keyword's position in hierarchy(ies) :

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