IKZF3 wt Allele

Preferred Label : IKZF3 wt Allele;

NCIt synonyms : AIO; IKAROS Family Zinc Finger 3 (Aiolos) wt Allele; Zinc Finger Protein, Subfamily 1A, 3 (Aiolos) Gene; AIOLOS; ZNFN1A3;

NCIt definition : Human IKZF3 wild-type allele is located in the vicinity of 17q21 and is approximately 99 kb in length. This allele, which encodes zinc finger protein Aiolos, is involved in the modulation of both lymphocyte development and transcription. Genetic variation may be associated with both the occurrence and relapse of acute lymphoblastic leukemia.;

GenBank Accession Number : AF129512;

PubMed : 19039135; 17344859;

Details

Origin ID

C80030;

UMLS CUI

C2697648;

OMIM relation
- Ikaros family zinc finger 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 17q21 [NCIt concept]
gene_is_element_in_pathway
- IL2-Mediated Signaling Pathway [NCIt concept]
- IL2RB Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcription [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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