Anti-Ganglioside GM2 Monoclonal Antibody BIW-8962

Preferred Label : Anti-Ganglioside GM2 Monoclonal Antibody BIW-8962;

NCIt synonyms : Anti-GM2 Monoclonal Antibody BIW-8962; Anti-Ganglioside GM2 Monoclonal Antibody BIW-896;

NCIt definition : A humanized anti-ganglioside GM2 (GM2) monoclonal antibody with potential antineoplastic and immunomodulating activities. Upon administration, anti-ganglioside GM2 monoclonal antibody BIW-8962 may activate an antibody dependent cellular cytotoxicity (ADCC) against GM2-expressing tumor cells. GM2 is a tumor associated antigen (TAA) overexpressed on the surface of many cancer cells, such as multiple myeloma (MM) cells and neuroblastoma cells.;

Molecule name : BIW-8962;

Details

Origin ID

C79795;

UMLS CUI

C2698143;

Currated CISMeF NLP mapping
- BIW-8962 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Antibody-Dependent Cellular Cytotoxicity [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Ganglioside GM2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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