Preferred Label : mTOR Kinase Inhibitor AZD8055;
NCIt related terms : AZD-8055;
NCIt definition : An inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic
activity. mTOR kinase inhibitor AZD8055 inhibits the serine/threonine kinase activity
of mTOR, resulting in decreased expression of mRNAs necessary for cell cycle progression,
which may induce cell cycle arrest and tumor cell apoptosis. mTOR phosphorylates transcription
factors, such as S6K1 and 4E-BP1, which stimulate protein synthesis and regulate cell
growth, proliferation, motility, and survival.;
UNII : 970JJ37FPW;
CAS number : 1009298-09-2;
Molecule name : AZD8055;
Origin ID : C78856;
UMLS CUI : C2697598;
Semantic type(s)
- concept_is_in_subset
- has_target
