Puromycin - CISMeF

Preferred Label : Puromycin;

NCIt synonyms : Puromicina; Puromycine; Stylomycin; L-3'-(alpha-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosine; Stillomycin; Adenosine, 3'-((2-amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-N,N-dimethyl-, (S)-; Adenosine, 3'-(alpha-amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyl-, L-; Puromycinum;

NCIt definition : An aminoglycoside antibiotic isolated from the bacterium Streptomyces alboniger. Acting as an analog of the 3' terminal end of aminoacyl-tRNA, puromycin incorporates itself into a growing polypeptide chain and causes its premature termination, thereby inhibiting protein synthesis. This agent has antimicrobial, antitrypanosomal, and antineoplastic properties; it is used as an antibiotic in cell culture. (NCI04);

UNII : 4A6ZS6Q2CL;

InChIKey : RXWNCPJZOCPEPQ-NVWDDTSBSA-N;

CAS number : 53-79-2;

Molecule name : P-638; CL 16536;

Chemical formula : C22H29N7O5;

NSC code : 3055;

ChEBI ID : CHEBI:17939;

Codes from synonyms : NSC0003055; 07447;

Details

Origin ID

C787;

UMLS CUI

C0034145;

Currated CISMeF NLP mapping
- puromycin [MeSH Descriptor]
- puromycin [MeSH concept]
- stylomycin [MeSH concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
UMLS correspondences (same concept)
- puromycin [MeSH concept]
- puromycin [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_salt_form
- Puromycin Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Puromycin Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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