puromycin - CISMeF

Preferred Label : puromycin;

MeSH definition : A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.;

CISMeF acronym : P638;

DeCS synonym : P638;

MeSH hyponym : puromycin hydrochloride; puromycin dihydrochloride; CL-13900; stylomycin; P-638; P 638; P638; CL 13900; CL13900;

MeSH CAS label : adenosine, 3'-((2-amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-N,N-dimethyl-, (S)-;

MeSH Related Number : puromycin dihydrochloride; 53-79-2 (Puromycin); 58-58-2 (di-HCl); puromycin hydrochloride; PGN54228S5;

Registry Number MeSH : 53-79-2;

Related CAS MeSH : 58-58-2 (Puromycin dihydrochloride); PGN54228S5 (Puromycin hydrochloride);

Wikipedia link : https://en.wikipedia.org/wiki/Puromycin;

Is substance : O;

UNII : 4A6ZS6Q2CL;

InChIKey : RXWNCPJZOCPEPQ-NVWDDTSBSA-N;

Details

Origin ID

D011691;

UMLS CUI

C0034145;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Puromycin [NCIt concept]
Pharmacological action(s)
- antimetabolites, antineoplastic [MeSH Descriptor]
- protein synthesis inhibitors [MeSH Descriptor]
- trypanocidal agents [MeSH Descriptor]
Record concept(s)
- CL-13900 [MeSH concept]
- P-638 [MeSH concept]
- puromycin [MeSH concept]
- puromycin dihydrochloride [MeSH concept]
- puromycin hydrochloride [MeSH concept]
- stylomycin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2'-deoxy-2'-fluoropuromycin [MeSH Supplementary Concept]
- 2'-deoxypuromycin [MeSH Supplementary Concept]
- 4-azidopuromycin [MeSH Supplementary Concept]
- 6-dimethylamino-9(3-(4-azido-L-beta-phenylalanylamino)- 3-deoxy-beta-ribofuranosyl)purine [MeSH Supplementary Concept]
- CCdApPuro [MeSH Supplementary Concept]
- N(6)-bis-demethylpuromycin [MeSH Supplementary Concept]
- N-(2-nitro-4-azidobenzoyl)puromycin [MeSH Supplementary Concept]
- N-acetylphenylalanylpuromycin [MeSH Supplementary Concept]
- N-iodoacetylpuromycin [MeSH Supplementary Concept]
- N6-bis-demethylated-puromycin [MeSH Supplementary Concept]
- O-demethylpuromycin [MeSH Supplementary Concept]
- O-propargyl-puromycin [MeSH Supplementary Concept]
- carbocyclic puromycin [MeSH Supplementary Concept]
- cyclohexylpuromycin [MeSH Supplementary Concept]
- cytidine-2'(3')-P-5'-puromycin [MeSH Supplementary Concept]
- fluorpuro [MeSH Supplementary Concept]
- methionylpuromycin [MeSH Supplementary Concept]
- peptidyl-puromycin [MeSH Supplementary Concept]
- peroxymycin-1 [MeSH Supplementary Concept]
- sparsopuromycin [MeSH Supplementary Concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
UMLS correspondences (same concept)
- Puromycin [NCIt concept]

Keyword's position in hierarchy(ies) :

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