" /> mTOR Kinase Inhibitor CERC-006 - CISMeF





Preferred Label : mTOR Kinase Inhibitor CERC-006;

NCIt synonyms : Mammalian Target of Rapamycin Kinase Inhibitor OSI-027; mTOR Kinase Inhibitor OSI-027;

NCIt related terms : OSI-027;

NCIt definition : An orally bioavailable mammalian target of rapamycin (mTOR) kinase inhibitor, with potential antineoplastic activity. Upon oral administration, mTOR kinase inhibitor CERC-006 binds to and inhibits both the raptor-mTOR (TOR complex 1 or TORC1) and the rictor-mTOR (TOR complex 2 or TORC2) complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. mTOR is a serine/threonine kinase that is upregulated in some tumors and plays an important role downstream in the PI3K/Akt/mTOR signaling pathway.;

UNII : 25MKH1SZ0M;

InChIKey : JROFGZPOBKIAEW-HAQNSBGRSA-N;

CAS number : 936890-98-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 936890-98-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : OSI-027; CERC-006; ASP 7486; AEVI-006; AEVI 006; ASP-7486; CERC 006;

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Keyword's position in hierarchy(ies) : arborescence

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15/05/2024


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