Prochlorperazine

Preferred Label : Prochlorperazine;

NCIt synonyms : 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine;

NCIt definition : A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. (NCI04);

Alternative definition : NCI-GLOSS: A drug used to prevent or reduce nausea and vomiting. It belongs to the family of drugs called antiemetics.;

UNII : YHP6YLT61T;

InChIKey : WIKYUJGCLQQFNW-UHFFFAOYSA-N;

CAS number : 58-38-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 58-38-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Compro;

Molecule name : SKF-4657; RP 6140;

Chemical formula : C20H24ClN3S;

ChEBI ID : CHEBI:8435;

Codes from synonyms : CDR0000045232; 420;

Details

Origin ID

C774;

UMLS CUI

C0033229;

Automatic exact mappings (from CISMeF team)
- Prochlorperazine [ICHI extension code]
See also inter- (CISMeF)
- Product containing prochlorperazine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Prochlorperazine [LOINC component]
- Prochlorperazine [ICD-11 Extension code]
- Prochlorperazine (substance) [SNOMED CT concept]
- Product containing prochlorperazine (medicinal product) [SNOMED CT concept]
- prochlorperazine [ATC Code]
- prochlorperazine [Substance BNPC]
- prochlorperazine [MeSH Descriptor]
- prochlorperazine [MeSH concept]
- prochlorperazine [SNOMED Notion]
Validated automatic mappings to BTNT
- prochlorperazine [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Prochlorperazine Edisylate [NCIt concept]
- Prochlorperazine Maleate [NCIt concept]
is_component_of_chemotherapy_regimen
- Carboplatin/Cyclosporine/Dipyridamole/Etoposide/Prochlorperazine [NCIt concept]
- Doxorubicin/Prochlorperazine [NCIt concept]
is_free_acid_or_base_form_of
- Prochlorperazine Edisylate [NCIt concept]
- Prochlorperazine Maleate [NCIt concept]

Keyword's position in hierarchy(ies) :

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