" /> Prochlorperazine Maleate - CISMeF





Preferred Label : Prochlorperazine Maleate;

NCIt synonyms : Prochlorperazine Dimaleate;

NCIt related terms : Compazine;

NCIt definition : The maleate salt form of prochlorperazine, a synthetic, piperazine phenothiazine derivative with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine binds to and blocks the postsynaptic dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. Prochlorperazine maleate also blocks anticholinergic and alpha-adrenergic receptors. Its antagonistic actions on the alpha-1 adrenergic receptors results in sedation, muscle relaxation, and hypotension.;

UNII : I1T8O1JTL6;

InChIKey : DSKIOWHQLUWFLG-SPIKMXEPSA-N;

CAS number : 84-02-6;

Drug name : Compazine;

Chemical formula : C20H24ClN3S.2C4H4O4;

NSC code : 17478;

ChEBI ID : CHEBI:8436;

Codes from synonyms : NSC0017478; 30909;

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19/06/2025


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