Pleural Malignant Mesothelioma

Preferred Label : Pleural Malignant Mesothelioma;

NCIt synonyms : Malignant Pleural Mesothelioma; Malignant Mesothelioma of the Pleura; Malignant Mesothelioma of Pleura; Pleural Diffuse Malignant Mesothelioma;

NCIt definition : A malignant neoplasm that arises from mesothelial cells in the pleura and shows a diffuse growth pattern. It arises on the parietal and sometimes visceral pleura as multiple small nodules that later become confluent and invade the chest wall adipose tissue and muscle. Asbestos exposure is the main cause for the development of pleural malignant mesothelioma. It usually affects patients over sixty years of age. The latency period is long. Patients usually present with pleural effusion, dyspnea and chest wall pain. Additional signs and symptoms include chills, sweating, weight loss, and weakness. Morphologic variants include epithelioid, desmoplastic, sarcomatoid, and biphasic mesothelioma. The clinical course is usually aggressive.;

Neoplastic status : Malignant;

Details

Origin ID

C7376;

UMLS CUI

C0812413;

Automatic exact mappings (from CISMeF team)
- Mesothelioma, Malignant [MeSH Descriptor]
Currated CISMeF NLP mapping
- Malignant Pleural Mesothelioma [MeSH concept]
- Malignant mesothelioma of pleura (disorder) [SNOMED CT concept]
- Malignant pleural mesothelioma [PASCAL descriptor]
- Mesothelioma of pleura [ICD-11 Subcategory]
- Pleural mesothelioma malignant [MedDRA Preferred Term]
- malignant pleural mesothelioma [DO Concept]
- pleural malignant mesothelioma [Disease (Nov.)]
- pleural mesothelioma malignant [TUV Concept]
- pleural mesothelioma malignant [TUV Term]
DO Cross reference
- malignant pleural mesothelioma [DO Concept]
Disease may have findings
- Anorexia [NCIt concept]
- Chest Pain [NCIt concept]
- Chills [NCIt concept]
- Dyspnea [NCIt concept]
- Fatigue [NCIt concept]
- Malaise [NCIt concept]
- Pleural Effusion [NCIt concept]
- Sweating [NCIt concept]
- Weight Loss [NCIt concept]
Excludes anatomical site(s)
- Neck [NCIt concept]
Has associated anatomic sites
- Pleural Cavity [NCIt concept]
- Respiratory System [NCIt concept]
- Thoracic Cavity [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Malignant mesothelioma of pleura (disorder) [SNOMED CT concept]
- Malignant pleural mesothelioma [PASCAL descriptor]
- Mesothelioma of pleura [ICD-10 Sub-category]
- Mesothelioma of pleura [ICD-11 Subcategory]
- Pleural mesothelioma [HPO term]
- Pleural mesothelioma malignant [MedDRA Preferred Term]
- malignant pleural mesothelioma [DO Concept]
- pleural malignant mesothelioma [Disease (Nov.)]
- pleural mesothelioma malignant [TUV Concept]
- pleural mesothelioma malignant [TUV Term]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Mesothelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Mesothelial Cell [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Mesothelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Mesothelium [NCIt concept]
- Pleura [NCIt concept]
disease_has_primary_anatomic_site
- Pleural Cavity [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 15q [NCIt concept]
- Gain of Chromosome 1q [NCIt concept]
- Gain of Chromosome 5p [NCIt concept]
- Gain of Chromosome 7p [NCIt concept]
- Gain of Chromosome 8q [NCIt concept]
- Loss of Chromosome 1 [NCIt concept]
- Loss of Chromosome 17p [NCIt concept]
- Loss of Chromosome 3 [NCIt concept]
- Loss of Chromosome 9 [NCIt concept]
- Monosomy 22 [NCIt concept]
disease_may_have_molecular_abnormality
- CDKN2A Gene Inactivation [NCIt concept]
- GPC3 Gene Inactivation [NCIt concept]
- NF2 Gene Mutation [NCIt concept]

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