Thyroid Transcription Factor 1

Preferred Label : Thyroid Transcription Factor 1;

NCIt synonyms : Homeobox protein Nkx-2.1; Homeobox protein NK-2 homolog A; Thyroid Transcription Factor; TTF-1; Thyroid nuclear factor 1; NKX2-1;

NCIt definition : Thyroid transcription factor 1 (371 aa, 39 kDa) is encoded by the human NKX2-1 gene. This protein is involved in transcriptional regulation.;

Details

Origin ID

C73445;

UMLS CUI

C1452466;

Currated CISMeF NLP mapping
- thyroid nuclear factor 1 [MeSH concept]
OMIM relation
- Nk2 homeobox 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NKX2-1 protein, human [MeSH concept]
- NKX2-1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- NKX2-1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Homeobox Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Homeo Domain [NCIt concept]
gene_product_is_element_in_pathway
- FOXA2 and FOXA3 Transcription Factor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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