" /> NONO wt Allele - CISMeF





Preferred Label : NONO wt Allele;

NCIt synonyms : Non-POU Domain Containing, Octamer-Binding wt Allele; P54; P54NRB; NMT55; NRB54;

NCIt definition : Human NONO wild-type allele is located in the vicinity of Xq13.1 and is approximately 18 kb in length. This allele, which encodes non-POU domain containing, octamer-binding protein, may play a role in the mediation of transcription, RNA splicing and DNA secondary structure. The gene can be involved in an inversion inv(X)(p11.2;q12) with the TFE3 gene in some papillary renal cell carcinomas.;

NCIt note : A complex of the NONO gene product and the SFPQ gene product may play a role in both RNA splicing and the nuclear retention of defective RNAs. (FEBS Lett. 2002; 531:109-14.);

GenBank Accession Number : NM_007363;

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30/07/2025


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