Naloxone Hydrochloride

Preferred Label : Naloxone Hydrochloride;

NCIt synonyms : Naloxone;

NCIt related terms : Narcan;

NCIt definition : The hydrochloride salt of naloxone, a thebaine derivate with opioid antagonist activity. Naloxone binds to opioid receptors in the CNS in a competitive manner, reversing or inhibiting characteristic opioid effects, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence. This agent binds to mu-opioid receptors with a high affinity, and a lesser degree to kappa- and gamma-opioid receptors.;

UNII : F850569PQR;

InChIKey : RGPDIGOSVORSAK-STHHAXOLSA-N;

CAS number : 357-08-4;

Drug name : Narcan;

Chemical formula : C19H21NO4.HCl;

NSC code : 70413;

Codes from synonyms : NSC0070413;

Détails

Origin ID

C678;

UMLS CUI

C0700549;

Automatic exact mappings (from CISMeF team)
- Naloxone [ICHI extension code]
- naloxone [MeSH Descriptor]
- naloxone [Substance BNPC]
- naloxone [ATC Code]
See also inter- (CISMeF)
- Product containing naloxone (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Naloxone Hydrochloride [MeSH concept]
- Naloxone hydrochloride [Substance BNPC]
- Naloxone hydrochloride (substance) [SNOMED CT concept]
- naloxone hydrochloride [SNOMED Notion]
Validated automatic mappings to NTBT
- Naloxone [LOINC component]
- Naloxone [ICD-11 Extension code]
- Naloxone [SMS substance]
- Naloxone (substance) [SNOMED CT concept]
- naloxone [MeSH Descriptor]
- naloxone [Substance BNPC]
- naloxone [SNOMED Notion]
- naloxone [ATC Code]
- naloxone [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Naloxone [NCIt concept]
is_salt_form_of
- Naloxone [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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