" /> Naloxone Hydrochloride - CISMeF





Preferred Label : Naloxone Hydrochloride;

NCIt synonyms : Naloxone;

NCIt related terms : Narcan;

NCIt definition : The hydrochloride salt of naloxone, a thebaine derivate with opioid antagonist activity. Naloxone binds to opioid receptors in the CNS in a competitive manner, reversing or inhibiting characteristic opioid effects, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence. This agent binds to mu-opioid receptors with a high affinity, and a lesser degree to kappa- and gamma-opioid receptors.;

UNII : F850569PQR;

InChIKey : RGPDIGOSVORSAK-STHHAXOLSA-N;

CAS number : 357-08-4;

Drug name : Narcan;

Chemical formula : C19H21NO4.HCl;

NSC code : 70413;

Codes from synonyms : NSC0070413;

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27/07/2025


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