Hydroxystilbamidine Isethionate

Preferred Label : Hydroxystilbamidine Isethionate;

NCIt definition : The isethionate salt form of hydroxystilbamidine, a cationic dye with antifungal, antitrypanosomal, antimalarial, and carcinostatic activities. Hydroxystilbamidine is able to bind to DNA and RNA in a non-intercalating manner, and is a powerful inhibitor of ribonucleases, thereby impeding cellular processes in protozoa. This agent was also shown to bind to lysosomes and induced a large number of lysosome-like bodies and secretion granules in trypanosome.;

UNII : 0163PVD2QZ;

InChIKey : XVTQTNAKZYLTNZ-UHFFFAOYSA-N;

CAS number : 533-22-2;

Chemical formula : C16H16N4O.2C2H6O4S;

Details

Origin ID

C65871;

UMLS CUI

C0304340;

Currated CISMeF NLP mapping
- Hydroxystilbamidine isethionate (substance) [SNOMED CT concept]
- hydroxystilbamidine isethionate [SNOMED Notion]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Hydroxystilbamidine isethionate (substance) [SNOMED CT concept]
- hydroxystilbamidine isethionate [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Hydroxystilbamidine [NCIt concept]
is_salt_form_of
- Hydroxystilbamidine [NCIt concept]

Keyword's position in hierarchy(ies) :

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