Hydroxystilbamidine

Preferred Label : Hydroxystilbamidine;

NCIt definition : A cationic dye with antifungal, antitrypanosomal, antimalarial, and carcinostatic activities. Hydroxystilbamidine is able to bind to DNA and RNA in a non-intercalating manner, and is a powerful inhibitor of ribonucleases, thereby impeding cellular processes in protozoa. This agent was also shown to bind to and stablize trypanosomal lysosomes. Hydroxystilbamidine is commonly used as a diagnostic agent in neuroanatomy and as a histochemical stain.;

UNII : 39J262E49W;

InChIKey : TUESWZZJYCLFNL-DAFODLJHSA-N;

CAS number : 495-99-8;

Chemical formula : C16H16N4O;

Details

Origin ID

C65870;

UMLS CUI

C0063195;

Automatic exact mappings (from CISMeF team)
- Hydroxystilbamidine [ICHI extension code]
Currated CISMeF NLP mapping
- Hydroxystilbamidine [ICD-11 Extension code]
- hydroxystilbamidine [MeSH concept]
- hydroxystilbamidine [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Hydroxystilbamidine [ICD-11 Extension code]
- hydroxystilbamidine [MeSH Supplementary Concept]
- hydroxystilbamidine [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Hydroxystilbamidine Isethionate [NCIt concept]
is_free_acid_or_base_form_of
- Hydroxystilbamidine Isethionate [NCIt concept]

Keyword's position in hierarchy(ies) :

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