NCIt definition : A prodrug of etilefrine, an adrenergic agonist with vasoconstrictive activity. Etilefrine
pivalate is hydrolyzed to etilefrine, which binds to and activates alpha-1-adrenergic
receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction
and leads to a decrease in venous pooling and increase in blood pressure. This agent
may also stimulate beta-1 adrenergic receptors leading to positive chronotropic and
inotropic effects.;