NCIt definition : Folliculin protein (579 aa, 64 kDa) is encoded by the human FLCN gene. This protein
is purported to play a role in tumor suppresion, but an exact function has yet to
be identified. Mutations and truncations in the protein have been implicated in the
pathogenesis of fibrofolliculoma formation, Birt-Hogg-Dube syndrome, and colorectal
tumorigenesis.;