Hydrocodone - CISMeF

Preferred Label : Hydrocodone;

NCIt synonyms : Hydrocodone Base;

NCIt definition : A semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and activates the mu-opioid receptor in the central nervous system (CNS). This leads to analgesia, euphoria, respiratory depression, miosis, decreased gastrointestinal motility, cough suppression and physical dependence. Hydrocodone is converted to hydromorphone by the cytochrome P450 enzyme CYP2D6.;

UNII : 6YKS4Y3WQ7;

InChIKey : LLPOLZWFYMWNKH-CMKMFDCUSA-N;

CAS number : 125-29-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 125-29-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C18H21NO3;

ChEBI ID : CHEBI:5779;

Details

Origin ID

C62033;

UMLS CUI

C0020264;

Currated CISMeF NLP mapping
- HYDROcodone [LOINC component]
- Hydrocodone [ICD-11 Extension code]
- Hydrocodone (substance) [SNOMED CT concept]
- Product containing hydrocodone (medicinal product) [SNOMED CT concept]
- hydrocodone [Substance BNPC]
- hydrocodone [MeSH Descriptor]
- hydrocodone [MeSH concept]
- hydrocodone [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- HYDROcodone [LOINC component]
- Hydrocodone [ICD-11 Extension code]
- Hydrocodone (substance) [SNOMED CT concept]
- Product containing hydrocodone (medicinal product) [SNOMED CT concept]
- hydrocodone [ATC Code]
- hydrocodone [Substance BNPC]
- hydrocodone [MeSH concept]
- hydrocodone [SNOMED Notion]
- hydrocodone [MeSH Descriptor]
Validated automatic mappings to BTNT
- hydrocodone [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2D6 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Hydrocodone Bitartrate [NCIt concept]
has_target
- Mu-Type Opioid Receptor [NCIt concept]
is_free_acid_or_base_form_of
- Hydrocodone Bitartrate [NCIt concept]

Keyword's position in hierarchy(ies) :

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