Flecainide - CISMeF

Preferred Label : Flecainide;

NCIt synonyms : Flecainide Base;

NCIt definition : A synthetic agent derived from trifluoroethoxy-benzamide exhibiting antiarrhythmic and local anesthetic activity. As a class Ic antiarrhythmic that blocks sodium channels, flecainide depresses polarization phase 0 and decreases the induction velocity of the His-Purkinje system. It also decreases phase 4 slope and increases the depolarization threshold. (NCI04);

Alternative definition : NCI-GLOSS: A drug that is used to treat abnormal heart rhythms. It may also relieve neuropathic pain, the burning, stabbing, or stinging pain that may arise from damage to nerves caused by some types of cancer or cancer treatment.;

UNII : K94FTS1806;

InChIKey : DJBNUMBKLMJRSA-UHFFFAOYSA-N;

CAS number : 54143-55-4;

Chemical formula : C17H20F6N2O3;

Codes from synonyms : NSC0719273; CDR0000045381;

Details

Origin ID

C62029;

UMLS CUI

C0016229;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Flecainide [ICD-11 Extension code]
- Flecainide [LOINC component]
- Flecainide (substance) [SNOMED CT concept]
- Product containing flecainide (medicinal product) [SNOMED CT concept]
- flecainide [ATC Code]
- flecainide [SNOMED Notion]
- flecainide [MeSH concept]
- flecainide [MeSH Descriptor]
Validated automatic mappings to BTNT
- flecainide [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2D6 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Flecainide Acetate [NCIt concept]
is_free_acid_or_base_form_of
- Flecainide Acetate [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients