NCIt definition : The calcium salt form of rosuvastatin, a statin with antilipidemic activity. Rosuvastatin
selectively and competitively binds to and inhibits hepatic hydroxymethyl-glutaryl
coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA
to mevalonate, a precursor of cholesterol. This leads to a decrease in hepatic cholesterol
levels and increase in uptake of LDL cholesterol.;
Alternative definition : NCI-GLOSS: A drug used to lower the amount of cholesterol and other harmful substances,
such as triglycerides, in the blood. It is also being studied in the prevention and
treatment of some types of cancer and other conditions. Crestor blocks an enzyme that
helps make cholesterol in the body and it helps break down cholesterol. It also may
cause cancer cells to die and may inhibit the growth of blood vessels that cancer
cells need to grow. It is a type of HMG-CoA reductase inhibitor and a type of statin.;
UNII : 83MVU38M7Q;
InChIKey : LALFOYNTGMUKGG-BGRFNVSISA-L;
CAS number : 147098-20-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 147098-20-2
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G-SRS /a ;
Drug name : Crestor;
Chemical formula : 2C22H27FN3O6S.Ca;
Codes from synonyms : CDR0000663321; CDR0000663322; 50551;