Preferred Label : Ketamine;

NCIt definition : A cyclohexanone derivative with analgesic and anesthetic properties. Although its mechanism of action is not well understood, ketamine appears exerts complex pharmacological actions including inhibition of biogenic amine uptake, binding to opioid receptors, and inhibition of N-methyl D-aspartate (NMDA) receptors. Because of the involvement of spinal NMDA receptors in the process of central sensitization, this agent may reduce pain perception and induce sedation.;

Alternative definition : NCI-GLOSS: A drug used to cause a loss of feeling and awareness and to induce sleep in patients having surgery. It is also being studied in the treatment of nerve pain caused by chemotherapy. Ketamine blocks pathways to the brain that are involved in sensing pain. It is a type of general anesthetic.;

UNII : 690G0D6V8H;

InChIKey : YQEZLKZALYSWHR-UHFFFAOYSA-N;

CAS number : 6740-88-1;

Chemical formula : C13H16ClNO;

ChEBI ID : CHEBI:6121;

Codes from synonyms : CDR0000557357;

Details


Keyword's position in hierarchy(ies) : arborescence

Main resources

You can consult :


https://www.has-sante.fr/jcms/p_3470372/fr/ketamine-panpharma-ketamine-anesthesie
2023
false
false
false
France
evaluation of the transparency committee
anesthesia
lack of sensation
Ketamine
FBXW4 wt Allele
ketamine
Anesthesia Procedure
Benzocaine
Ketamine Hydrochloride

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28/05/2025


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