Ketamine Hydrochloride

Preferred Label : Ketamine Hydrochloride;

NCIt synonyms : Ketamine HCl;

NCIt related terms : Ketamine; Ketalar;

NCIt definition : The hydrochloride salt of a synthetic derivative of cyclohexanone with analgesic and anesthetic activities. Although its mechanism of action is not well understood, ketamine appears to non-competitively block N-methyl-D-aspartate (NMDA) receptors and may interact with opioid mu receptors and sigma receptors, thereby reducing pain perception, inducing sedation, and producing dissociative anesthesia.;

Alternative definition : NCI-GLOSS: A drug used to cause a loss of feeling and awareness and to induce sleep in patients having surgery. It is also being studied in the treatment of nerve pain caused by chemotherapy. Ketalar blocks pathways to the brain that are involved in sensing pain. It is a type of general anesthetic.;

UNII : O18YUO0I83;

InChIKey : VCMGMSHEPQENPE-UHFFFAOYSA-N;

CAS number : 1867-66-9;

Drug name : Ketalar;

Chemical formula : C13H16ClNO.HCl;

ChEBI ID : CHEBI:650657;

Codes from synonyms : CDR0000589408; CDR0000589409;

Details

Origin ID

C29142;

UMLS CUI

C0700541;

Automatic exact mappings (from CISMeF team)
- ketamine [MeSH Descriptor]
- ketamine [ATC Code]
Currated CISMeF NLP mapping
- Ketamine hydrochloride [Substance BNPC]
- Ketamine hydrochloride [SMS substance]
- Ketamine hydrochloride (substance) [SNOMED CT concept]
- ketamine hydrochloride [MeSH concept]
- ketamine hydrochloride [SNOMED Notion]
See also inter- (CISMeF)
- Ketamine hydrochloride (product) [Inactive SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Ketamine [LOINC component]
- Ketamine [ICD-11 Extension code]
- Ketamine [SMS substance]
- Ketamine (substance) [SNOMED CT concept]
- ketamine [MeSH Descriptor]
- ketamine [Substance BNPC]
- ketamine [MeSH concept]
concept_is_in_subset
- CPTAC Baseline Medical Forms Terminology [NCIt concept]
- CPTAC Surgery-Anesthesia Form [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Ketamine [NCIt concept]
is_salt_form_of
- Ketamine [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients