Dantrolene Sodium

Preferred Label : Dantrolene Sodium;

NCIt definition : The sodium salt form of dantrolene, a hydantoin derivative and direct-acting skeletal muscle relaxant. Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1, and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from the sarcoplasmic reticulum, an essential step in muscle contraction.;

UNII : 287M0347EV;

InChIKey : LTWQNYPDAUSXBC-CDJGKPBYSA-L;

CAS number : 14663-23-1;

Chemical formula : 2C14H9N4O5.2Na.7H2O;

ChEBI ID : CHEBI:184644; CHEBI:4318;

Details

Origin ID

C61698;

UMLS CUI

C0010977;

Automatic exact mappings (from CISMeF team)
- dantrolene [Substance BNPC]
- dantrolene [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Dantrolene [NCIt concept]
is_salt_form_of
- Dantrolene [NCIt concept]

Keyword's position in hierarchy(ies) :

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