Dantrolene - CISMeF

Preferred Label : Dantrolene;

NCIt definition : A hydantoin derivative and direct-acting skeletal muscle relaxant. Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1, and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from the sarcoplasmic reticulum, an essential step in muscle contraction.;

UNII : F64QU97QCR;

InChIKey : OZOMQRBLCMDCEG-VIZOYTHASA-N;

CAS number : 7261-97-4;

Chemical formula : C14H10N4O5;

ChEBI ID : CHEBI:4317;

Details

Origin ID

C61697;

UMLS CUI

C0010976;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Dantrolene [ICD-11 Extension code]
- Dantrolene [LOINC component]
- Dantrolene (substance) [SNOMED CT concept]
- Product containing dantrolene (medicinal product) [SNOMED CT concept]
- dantrolene [ATC Code]
- dantrolene [Substance BNPC]
- dantrolene [SNOMED Notion]
- dantrolene [MeSH concept]
- dantrolene [MeSH Descriptor]
Validated automatic mappings to BTNT
- dantrolene [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Dantrolene Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Dantrolene Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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