Amiloride - CISMeF

Preferred Label : Amiloride;

NCIt definition : A synthetic pyrazine derivative with antikaliuretic and diuretic properties. Amiloride inhibits sodium channels located in the distal tubules and collecting ducts of the kidney, thereby preventing the absorption of sodium and increasing its excretion along with water, to produce naturesis. In response to the hypernatremic conditions in the kidney, the plasma membrane becomes hyperpolarized and electrochemical forces are reduced, which then prevents the excretion of potassium and hydrogen into the lumen.;

UNII : 7DZO8EB0Z3;

InChIKey : XSDQTOBWRPYKKA-UHFFFAOYSA-N;

CAS number : 2609-46-3;

Chemical formula : C6H8ClN7O;

ChEBI ID : CHEBI:2639;

Codes from synonyms : 01107;

PubMed : 9563749;

Details

Origin ID

C61633;

UMLS CUI

C0002502;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Amiloride [ICD-11 Extension code]
- Amiloride (substance) [SNOMED CT concept]
- Product containing amiloride (medicinal product) [SNOMED CT concept]
- aMILoride [LOINC component]
- amiloride [ATC Code]
- amiloride [Substance BNPC]
- amiloride [MeSH Descriptor]
- amiloride [MeSH concept]
- amiloride [SNOMED Notion]
Validated automatic mappings to BTNT
- amiloride [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Amiloride Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Amiloride Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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