" /> Amiloride Hydrochloride - CISMeF





Preferred Label : Amiloride Hydrochloride;

NCIt synonyms : N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide Monohydrochloride; Pyrazinecarboxamide, N-Amidino-3,5-diamino-6-chloro-, Monohydrochloride;

NCIt definition : The hydrochloride salt of amiloride, a synthetic pyrazine derivative with antikaliuretic and diuretic properties. Amiloride inhibits sodium channels located in the distal tubules and collecting ducts of the kidney, thereby preventing the absorption of sodium and increasing its excretion along with water, to produce naturesis. In response to the hypernatremic conditions in the kidney, the plasma membrane becomes hyperpolarized and electrochemical forces are reduced, which then prevents the excretion of potassium and hydrogen into the lumen.;

UNII : FZJ37245UC;

CAS number : 17440-83-4;

Drug name : Midamor;

Molecule name : CCRIS 5959; KM87O;

Chemical formula : C6H8ClN7O.ClH.2H2O;

ChEBI ID : CHEBI:2640;

Codes from synonyms : 32076;

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09/05/2025


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