Metformin - CISMeF

Preferred Label : Metformin;

NCIt synonyms : 1,1-Dimethylbiguanide; N,N-Dimethylimidodicarbonimidic Diamide; N,N-dimethylbiguanide;

NCIt definition : An agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. Metformin is associated with a very low incidence of lactic acidosis. This agent helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain, and prevents the cardiovascular complications of diabetes. Metformin is not metabolized and is excreted unchanged by the kidneys.;

Alternative definition : NCI-GLOSS: The active ingredient in a drug used to treat diabetes mellitus (a condition in which the body cannot control the level of sugar in the blood). It is also being studied in the treatment of cancer. It decreases the amount of glucose (a type of sugar) released into the bloodstream from the liver and increases the body's use of the glucose. Metformin is a type of antidiabetic agent.; ACC/AHA: A specific agent belonging to the biguanide class of antihyperglycemic agents;

UNII : 9100L32L2N;

InChIKey : XZWYZXLIPXDOLR-UHFFFAOYSA-N;

CAS number : 657-24-9;

Chemical formula : C4H11N5;

ChEBI ID : CHEBI:6801;

Codes from synonyms : CDR0000631043;

Details

Origin ID

C61612;

UMLS CUI

C0025598;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Metformin [ICD-11 Extension code]
- Metformin (substance) [SNOMED CT concept]
- Product containing metformin (medicinal product) [SNOMED CT concept]
- metFORMIN [LOINC component]
- metformin [ATC Code]
- metformin [Substance BNPC]
- metformin [MeSH Descriptor]
- metformin [MeSH concept]
Validated automatic mappings to BTNT
- metformin [ATC Code]
concept_is_in_subset
- ACC/AHA COVID-19 Appendix Variables [NCIt concept]
- ACC/AHA Cardiovascular and Noncardiovascular Complications of COVID-19 Terminology [NCIt concept]
- Appendix 8: Pharmacological Therapy Terminology [NCIt concept]
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
- Therapies for Preexisting Cardiovascular Disease (Patient Taking Prior to Admission) Terminology [NCIt concept]
has_salt_form
- Metformin Hydrochloride [NCIt concept]
has_target
- 5'-AMP-Activated Protein Kinase [NCIt concept]
- NADH Dehydrogenase (Ubiquinone) [NCIt concept]
is_free_acid_or_base_form_of
- Metformin Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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