" /> Mapatumumab - CISMeF





Preferred Label : Mapatumumab;

NCIt synonyms : Anti-TRAIL R1-mAb; TRM-1 mAb;

NCIt related terms : HGS-ETR1;

NCIt definition : A fully human agonistic monoclonal antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor-1 (TRAIL-R1) with apoptosis promoting and potential antitumor activities. TRAIL-R1 is a cell surface receptor expressed on many malignant cell types. Mapatumumab selectively binds to and activates the TRAIL cell receptor, thereby inducing apoptosis and reducing tumor growth.;

Alternative definition : NCI-GLOSS: A substance being studied in the treatment of some types of cancer. It binds to a protein called TRAIL R1 on the surface of some tumor cells. This may kill the tumor cells. Anti-TRAIL R1-mAb is a type of monoclonal antibody.;

UNII : WZ1025JPGR;

CAS number : 658052-09-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 658052-09-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : HGS-ETR1;

Codes from synonyms : CDR0000641131; CDR0000643596; 320;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
10/05/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.