mapatumumab - CISMeF

Preferred Label : mapatumumab;

MeSH note : a fully human IgG1 agonistic mAb that exclusively targets tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R1) which is overexpressed on the surface of many tumors;

MeSH hyponym : TRM-1 HGS-ETR1; HGS1012; TRAIL-R1 MAB; TRM-1;

Is substance : O;

UNII : WZ1025JPGR;

Details

Origin ID

C507357;

UMLS CUI

C1665688;

Currated CISMeF NLP mapping
- Mapatumumab [NCIt concept]
MeSH term(s) associated for indexing
- antibodies, monoclonal [MeSH Descriptor]
- antibodies, monoclonal, humanized [MeSH Descriptor]
Pharmacological action(s)
- antineoplastic agents [MeSH Descriptor]
Record concept(s)
- HGS-1012 [MeSH concept]
- HGS-ETR1 [MeSH concept]
- TRAIL-R 1MAB [MeSH concept]
- mapatumumab [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Mapatumumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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