Recombinant Interferon Gamma

Preferred Label : Recombinant Interferon Gamma;

NCIt synonyms : Gamma Interferon (GEN); Gamma-Interferon; Interferon, Gamma; Interferon Gamma (BIO); Ginterferon; Gamma Interferon-SCH; IFN-g; Therapeutic Interferon Gamma;

NCIt related terms : INTERFERON GAMMA;

NCIt definition : A recombinant therapeutic agent which is chemically identical to or similar to the endogenous lymphokine interferon gamma (IFN-gamma) with antineoplastic, immunoregulatory, and antiviral activities. Therapeutic IFN-gamma binds to and activates the cell-surface IFN-gamma receptor, stimulating antibody-dependent cytotoxicity and enhances natural killer cell attachment to tumor cells. This agent also activates caspases, thereby inducing apoptosis in malignant cells. (NCI04);

UNII : P050J5FWC5;

CAS number : 82115-62-6;

NSC code : 635256; 600662;

Codes from synonyms : NSC0635256;

Details

Origin ID

C583;

UMLS CUI

C3539881;

Automatic exact mappings (from CISMeF team)
- Interferon gamma [ICD-11 Extension code]
- Interferon gamma [SMS substance]
- Interferon gamma low [MedDRA LLT]
- Interferon, gamma [OMIM gene]
- Product containing interferon gamma (medicinal product) [SNOMED CT concept]
- interferon gamma [HGNC gene]
- interferon gamma [COVID-19 Thesaurus concept]
- interferon gamma [ORDO Gene]
- interferon-gamma receptor binding [GO term]
- interferon-γ [Blood Transfusion thesaurus concept]
False automatic mappings
- interferon gamma (1-39) [MeSH concept]
- interferon gamma (1-39) [MeSH Supplementary Concept]
- interferon-gamma (95-133) [MeSH concept]
- interferon-gamma (95-133) [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Interferon gamma (substance) [SNOMED CT concept]
- Product containing interferon gamma (medicinal product) [SNOMED CT concept]
- interferon gamma [ATC Code]
- interferon-gamma [MeSH Descriptor]
Validated automatic mappings to BTNT
- interferon gamma [ATC Code]
chemical_or_drug_affects_gene_product
- Interferon Gamma Receptor Complex [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Cytokine Receptor Activation [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Antibody-Dependent Cellular Cytotoxicity [NCIt concept]
- Immunopotentiation [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- AUT-OV-ALVAC-hB7.1/Interferon Gamma [NCIt concept]
- Autologous Dendritic Cells/Candida Albicans Skin Test Reagent/CD40-Ligand/gp100 Antigen/Interferon Gamma/Interleukin-4/MART-1 Antigen/Sargramostim/Tyrosinase Peptide [NCIt concept]
- Bispecific Antibody 520C9XH22/Interferon Gamma [NCIt concept]
- Cyclosporine/Interferon Gamma [NCIt concept]
- Cyclosporine/Interferon Gamma/Interleukin-2 [NCIt concept]
- Fluorouracil/Interferon Alfa/Interferon Gamma/Leucovorin Calcium [NCIt concept]
- Interferon Alfa/Interferon Gamma [NCIt concept]
- Interferon Beta/Interferon Gamma [NCIt concept]
- Interferon Gamma/Interleukin-1-Beta/Interleukin-2/Sargramostim/Tumor Necrosis Factor [NCIt concept]
- Interferon Gamma/Interleukin-2 [NCIt concept]
- Interferon Gamma/Interleukin-2/Melphalan/Tumor Necrosis Factor [NCIt concept]
- Interferon Gamma/Interleukin-2/Tumor Infiltrating Lymphocytes [NCIt concept]
- Interferon Gamma/Levamisole [NCIt concept]
- Interferon Gamma/Macrophage Colony-Stimulating Factor [NCIt concept]
- Interferon Gamma/Melphalan/Tumor Necrosis Factor [NCIt concept]
- Interferon Gamma/Monoclonal Antibody CC49 [NCIt concept]
- Interferon Gamma/Sargramostim [NCIt concept]
- Interferon Gamma/Tumor Necrosis Factor [NCIt concept]
- Interferon Gamma/Voriconazole [NCIt concept]

Keyword's position in hierarchy(ies) :

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