Heparin - CISMeF

Preferred Label : Heparin;

NCIt synonyms : Unfractionated Heparin; UFH;

NCIt definition : A sulfur-rich glycosaminoglycan with anticoagulant property. Heparin binds to antithrombin III to form a heparin-antithrombin III complex. The complex binds to and irreversibly inactivates thrombin and other activated clotting factors, such as factors IX, X, XI, and XII, thereby preventing the polymerization of fibrinogen to fibrin and the subsequent formation of clots.;

Alternative definition : NCI-GLOSS: A substance that slows the formation of blood clots. Heparin is made by the liver, lungs, and other tissues in the body and can also made in the laboratory. Heparin may be injected into muscle or blood to prevent or break up blood clots. It is a type of anticoagulant.; ACC/AHA: Heparin is an indirect thrombin inhibitor composed of a mixture of heterogeneous mucopolysaccharides with a molecular weight of 5-30 kDa.;

UNII : T2410KM04A;

CAS number : 9005-49-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 9005-49-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : (C14H18NO11)n.2(C12H16NO13S)n.3HO3S;

ChEBI ID : CHEBI:28304;

Codes from synonyms : CDR0000045321; 521;

Details

Origin ID

C539;

UMLS CUI

C0019134;

Automatic exact mappings (from CISMeF team)
- Heparin [ICD-11 Extension code]
- Heparin given [LOINC component]
- Heparin sodium [ICD-11 Extension code]
- Heparin unfractionated [LOINC component]
- LMW Heparin [LOINC component]
- heparin group [ATC Code]
- heparinizing [Artificial nutrition thesaurus concept]
- unfractionated heparin [SNOMED Notion]
See also inter- (CISMeF)
- Product containing heparin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Heparin [FMA entity]
- Heparin [LOINC component]
- Heparin (substance) [SNOMED CT concept]
- Heparin unfractionated [LOINC component]
- Product containing heparin (medicinal product) [SNOMED CT concept]
- Unfractionated heparin (substance) [Inactive SNOMED CT concept]
- heparin [ATC Code]
- heparin [ATC Code]
- heparin [ATC Code]
- heparin [Substance BNPC]
- heparin [MeSH Descriptor]
- heparin [MeSH concept]
- heparin [SNOMED Notion]
- unfractionated heparin [SNOMED Notion]
Validated automatic mappings to BTNT
- heparin [ATC Code]
- heparin [ATC Code]
- heparin [ATC Code]
concept_is_in_subset
- ACC/AHA COVID-19 Appendix Authorized Values [NCIt concept]
- ACC/AHA Cardiovascular and Noncardiovascular Complications of COVID-19 Terminology [NCIt concept]
- Appendix 8: Pharmacological Therapy Terminology [NCIt concept]
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
- Therapies for Supportive Care During COVID-19 Infection Terminology [NCIt concept]
has_salt_form
- Heparin Calcium [NCIt concept]
- Heparin Potassium [NCIt concept]
- Heparin Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Heparin Calcium [NCIt concept]
- Heparin Potassium [NCIt concept]
- Heparin Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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