" /> SPI1 wt Allele - CISMeF





Preferred Label : SPI1 wt Allele;

NCIt synonyms : Spleen Focus Forming Virus Proviral Integration Oncogene SPI1 Gene; Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene SPI1 Gene; Spleen Focus Forming Virus Proviral Integration Gene 1; SPI1; PU.1; SPI-1; OF; SFPI1; SPI-A; Spi-1 Proto-Oncogene wt Allele; SFFV Virus-Induced Murine Erythroleukemia Oncogene, Mouse, Homolog of Gene; AGM10; Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Gene; SPI1 Protooncogene Gene;

NCIt definition : The human SPI1 wild-type allele is located in the vicinity of 11p11.2 and is approximately 24 kb in length. This allele, which encodes transcription factor PU.1 protein, is involved in the activation of transcription by RNA polymerase II.;

NCIt note : The product of the SPI1 gene binds to the PU-box, a purine-rich DNA sequence (5'- GAGGAA-3') that can act as a lymphoid-specific enhancer of transcription (GeneCards).;

GenBank Accession Number : NM_003120;

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16/05/2024


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