IL6ST wt Allele

Preferred Label : IL6ST wt Allele;

NCIt synonyms : GP130 of the Rheumatoid Arthritis Antigenic Peptide-Bearing Soluble Form Gene; GP130; GP130-RAPS; IL6R-beta; CD130; GP130, Oncostatin M Receptor Gene; CDW130; Interleukin 6 Signal Transducer (GP130, Oncostatin M Receptor) Gene; Interleukin 6 Signal Transducer wt Allele;

NCIt definition : Human IL6ST wild-type allele is located in the vicinity of 5q11 and is approximately 60 kb in length. This allele, which encodes interleukin-6 receptor subunit beta protein, is involved in regulation of both ligand binding to cytokine receptors and cytokine-dependent signal transduction pathways.;

GenBank Accession Number : NM_002184;

Details

Origin ID

C52804;

UMLS CUI

C1705346;

Automatic exact mappings (from CISMeF team)
- 2-phenyl-5,5-dimethyltetrahydro-1,4-oxazine [MeSH Supplementary Concept]
- Interleukin 6 cytokine family signal transducer [OMIM gene]
- ciliary neurotrophic factor receptor activity [GO term]
- cytokine receptor gp130 [MeSH Descriptor]
- interleukin 6 cytokine family signal transducer [HGNC gene]
- interleukin-11 receptor activity [GO term]
- interleukin-6 receptor activity [GO term]
- leucine rich pentatricopeptide repeat containing [ORDO Gene]
Currated CISMeF NLP mapping
- obsolete gp130 [GO term]
OMIM relation
- Interleukin 6 cytokine family signal transducer [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 5: 55326520-55272452 [NCIt concept]
gene_in_chromosomal_location
- 5q11 [NCIt concept]
gene_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- ERBB2 Signaling Pathway [NCIt concept]
- IL27-Mediated Signaling Pathway [NCIt concept]
- IL6 Signaling Pathway [NCIt concept]
- IL6-Mediated Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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