APC2 wt Allele

Preferred Label : APC2 wt Allele;

NCIt synonyms : Adenomatosis Polyposis Coli 2 wt Allele; APCL; APCL wt Allele;

NCIt definition : Human APC2 wild-type allele is located in the vicinity of 19p13.3 and is approximately 23 kb in length. This allele, which encodes adenomatous polyposis coli protein 2, plays a role in the potentiation of the Wnt protein signaling pathway.;

GenBank Accession Number : NM_005883;

Details

Origin ID

C52459;

UMLS CUI

C1704956;

Automatic exact mappings (from CISMeF team)
- APC regulator of WNT signaling pathway 2 [ORDO Gene]
- Apc2 regulator of wnt signaling pathway 2 [OMIM gene]
OMIM relation
- Apc2 regulator of wnt signaling pathway 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 19: 1402288-1424237 [NCIt concept]
gene_in_chromosomal_location
- 19p13.3 [NCIt concept]
gene_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Basal Cell Carcinoma Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Hippo Signaling Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Signal Transduction [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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