GAB2 wt Allele

Preferred Label : GAB2 wt Allele;

NCIt synonyms : KIAA0571; GRB2-Associated Binding Protein 2 Gene; GRB2 Associated Binding Protein 2 wt Allele;

NCIt definition : Human GAB2 wild-type allele is located in the vicinity of 11q14.1 and is approximately 202 kb in length. This allele, which encodes GRB2-associated-binding protein 2, plays a role in hematopoetic cell receptor signal potentiation.;

NCIt note : GAB2 is expressed as two alternatively spliced transcripts.;

GenBank Accession Number : NM_012296;

Details

Origin ID

C52386;

UMLS CUI

C1708114;

Automatic exact mappings (from CISMeF team)
- Grb2-associated binding protein 2 [OMIM gene]
OMIM relation
- Grb2-associated binding protein 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 11: 77806414-77603990 [NCIt concept]
gene_in_chromosomal_location
- 11q13.3 [NCIt concept]
gene_is_element_in_pathway
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- IL2/PI3K Signaling Pathway [NCIt concept]
- IL2/STAT5 Signaling Pathway [NCIt concept]
- IL6-Mediated Signaling Pathway [NCIt concept]
- Neurotrophic Factor-Mediated NTRK1 Signaling Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
gene_plays_role_in_process
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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