" /> CYP2C8 wt Allele - CISMeF





Preferred Label : CYP2C8 wt Allele;

NCIt synonyms : CPC8; Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 wt Allele; P450 MP-12/MP-20;

NCIt definition : Human CYP2C8 wild-type allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, which encodes cytochrome P450 2C8 protein, plays a role in the metabolism of drugs and xenobiotics. Several allelic variants of the CYP2C8 gene contribute to the poor metabolizer phenotype.;

NCIt note : The poor metabolizer phenotype is characterized by the inability to use cytochrome P450-dependent metabolic pathways for drug elimination.;

GenBank Accession Number : NM_000770;

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28/04/2024


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