CYP2C18 wt Allele

Preferred Label : CYP2C18 wt Allele;

NCIt synonyms : CYP2C; CYP2C17; P450-6B/29C; CPCI; P450IIC17; Cytochrome P450, Family 2, Subfamily C, Polypeptide 18 wt Allele;

NCIt definition : Human CYP2C18 wild-type allele is located within 10q24 and is approximately 53 kb in length. This allele, which encodes cytochrome P450 2C18 protein, plays a role in the synthesis of cholesterol, steroids and other lipids. It is also involved in the metabolism of drugs and xenobiotics.;

NCIt note : This gene produces three distinct mRNA transcripts that result from exon skipping.;

GenBank Accession Number : NM_000772;

Details

Origin ID

C52357;

UMLS CUI

C1705793;

OMIM relation
- Cytochrome p450, subfamily iic, polypeptide 18 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 10: 9643368-96485514 [NCIt concept]
gene_in_chromosomal_location
- 10q24 [NCIt concept]
gene_is_element_in_pathway
- Arachidonic Acid Metabolism Pathway [NCIt concept]
- Drug Metabolism by Cytochrome P450 Pathway [NCIt concept]
- FOXA1 Transcription Factor Signaling Pathway [NCIt concept]
- Fatty Acid Metabolism Pathway [NCIt concept]
- Linoleic Acid Metabolism Pathway [NCIt concept]
- Metabolism of Xenobiotics by Cytochrome P450 Pathway [NCIt concept]
- Retinol Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- Detoxification [NCIt concept]
- Drug Metabolism [NCIt concept]
- Intermediary Metabolic Process [NCIt concept]
- Iron Chelation [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

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