NCIt synonyms : CYAR; CYP19; P-450AROM; CYPXIX; ARO; ARO1; CPV1; Cytochrome P450, Subfamily XIX Gene; Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 Gene; Cytochrome P450 Family 19 Subfamily A Member 1 wt Allele; Cytochrome P450, Subfamily XIX (Aromatization of Androgens) Gene;
NCIt definition : Human CYP19A1 wild-type allele is located in the vicinity of 15q21.2 and is approximately
131 kb in length. This allele, which encodes aromatase protein, is involved in the
biosynthesis of estrogen. Certain allelic variants of the CYP19A1 gene exhibit functional
mutations that result in enhanced aromatase activity which, in turn, causes familial
gynecomastia.;