HMGB2 wt Allele

Preferred Label : HMGB2 wt Allele;

NCIt synonyms : High Mobility Group Protein 2 Gene; HMG2 Gene; High-Mobility Group Box 2 wt Allele; Nonhistone Chromosomal Protein HMG2 Gene; HMG-2 Gene; High Mobility Group Box 2 Gene; High-Mobility Group (Nonhistone Chromosomal) Protein 2 Gene;

NCIt definition : Human HMGB2 wild-type allele is located within 4q31 and is approximately 3 kb in length. This allele, which encodes high mobility group protein B2, plays a role in the replication, repair and recombination of DNA.;

NCIt note : Autoantibodies to high mobility group protein B2, the product of the HMGB2 gene, have been detected in serum of patients with juvenile rheumatoid arthritis.;

GenBank Accession Number : NM_002129;

Détails

Origin ID

C52077;

UMLS CUI

C1708282;

OMIM relation
- High mobility group box 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 4: 174630322-174627518 [NCIt concept]
gene_in_chromosomal_location
- 4q31 [NCIt concept]
gene_is_element_in_pathway
- Apoptotic DNA Fragmentation Pathway [NCIt concept]
- Granzyme A Mediated Apoptosis Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Double Strand Break Repair [NCIt concept]
- Transcription [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- V(D)J Recombination [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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