NCIt definition : Human GH1 wild-type allele is located in the vicinity of 17q24.2 and is approximately
2 kb in length. This allele, which encodes somatotropin protein, plays a role in the
stimulation of insulin-like growth factor 1 secretion. It is also involved in the
positive regulation of amino acid uptake, protein synthesis, cell differentiation
and cell proliferation. Certain allelic variants of the GH1 gene are associated with
growth hormone deficiency and short stature.;