FNTA wt Allele

Preferred Label : FNTA wt Allele;

NCIt synonyms : FPTA; Farnesyltransferase, CAAX Box, Alpha wt Allele; PGGT1A; PTAR2;

NCIt definition : Human FNTA wild-type allele is located within 8p22-q11 and is approximately 29 kb in length. This allele, which encodes protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit protein, is involved in the post-translational modification of certain proteins via the addition of either a farnesyl group or geranylgeranyl group.;

NCIt note : The FNTA gene produces two RNA transcript variants via alternative splicing which, in turn, encode distinct protein isoforms.;

GenBank Accession Number : NM_002027;

Details

Origin ID

C52032;

UMLS CUI

C1705929;

Automatic exact mappings (from CISMeF team)
- Farnesyltransferase, caax box, alpha [OMIM gene]
OMIM relation
- Farnesyltransferase, caax box, alpha [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_has_physical_location
- 8: 43030641-43060080 [NCIt concept]
gene_in_chromosomal_location
- 8p22-q11 [NCIt concept]
gene_is_element_in_pathway
- N-Glycan Biosynthesis Pathway [NCIt concept]
- Terpenoid Biosynthesis Pathway [NCIt concept]
- Ubiquinone Biosynthesis Pathway [NCIt concept]
gene_plays_role_in_process
- Isoprenylation Process [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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