" /> Ganciclovir - CISMeF





Preferred Label : Ganciclovir;

NCIt synonyms : 2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6H-purin-6-one; Nordeoxyguanosine; 9-[(1,3-Dihydroxy-2-propoxy)methyl]guanine; 2'NDG; 2'-Nor-2'-deoxyguanosine; DHPG; GCV;

NCIt definition : A synthetic guanine derivative with antiviral activity. As the active metabolite of ganciclovir, ganciclovir-5-triphosphate (ganciclovir-TP) appears to inhibit viral DNA synthesis by competitive inhibition of viral DNA polymerases and incorporation into viral DNA, resulting in eventual termination of viral DNA elongation.;

Alternative definition : NCI-GLOSS: An antiviral agent used to prevent or treat cytomegalovirus infections that may occur when the body's immune system is suppressed. In gene therapy, ganciclovir is used with an altered herpes simplex virus-1 gene to kill advanced melanoma cells and brain tumor cells.;

UNII : P9G3CKZ4P5;

InChIKey : IRSCQMHQWWYFCW-UHFFFAOYSA-N;

CAS number : 82410-32-0;

Drug name : Cymevan; Virgan;

Chemical formula : C9H13N5O4;

NSC code : 759656;

ChEBI ID : CHEBI:465284;

Codes from synonyms : NSC0716361; CDR0000045303;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
08/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.