" /> Ganciclovir Sodium - CISMeF





Preferred Label : Ganciclovir Sodium;

NCIt synonyms : 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine, Monosodium Salt; DHPG sodium;

NCIt related terms : Cytovene; GCV Sodium;

NCIt definition : The sodium salt form of ganciclovir, a synthetic, antiviral, purine nucleoside analog with antiviral activity, especially against cytomegalovirus (CMV). Ganciclovir sodium is a prodrug that is phosphorylated and subsequently converted into its triphosphate form, the active metabolite ganciclovir-5-triphosphate (ganciclovir-TP), in the infected cells by cellular kinases. Ganciclovir-TP competes as a substrate with nucleotide triphosphates for viral DNA polymerase. Once it gets incorporated into DNA strand, it prevents further polymerization of DNA, thereby interfering with viral DNA replication.;

UNII : 02L083W284;

InChIKey : JJICLMJFIKGAAU-UHFFFAOYSA-M;

CAS number : 107910-75-8;

Drug name : Cymevene; Denosine; Cytovene-IV;

Molecule name : BIOLF-62; BW-759; BW-759U; RS-21592 Sodium;

Chemical formula : C9H12N5O4.Na;

Codes from synonyms : NSC0716361;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
10/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.