HTR2A wt Allele

Preferred Label : HTR2A wt Allele;

NCIt synonyms : 5-Hydroxytryptamine (Serotonin) Receptor 2A Gene; HTR2 Gene; 5-Hydroxytryptamine Receptor 2A wt Allele; HTR2; Serotonin 5-HT-2 Receptor Gene; 5-HT2A; 5-HT-2A Gene; 5-Hydroxytryptamine (Serotonin) Receptor 2A, G Protein-Coupled Gene;

NCIt definition : Human HTR2A wild-type allele is located within 13q14-q21 and is approximately 63 kb in length. This allele, which encodes 5-hydroxytryptamine 2A receptor protein, is involved in several processes that activate a PI-calcium second messenger system via G-protein association, such as tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.;

GenBank Accession Number : NM_000621;

Details

Origin ID

C51467;

UMLS CUI

C1708300;

Automatic exact mappings (from CISMeF team)
- receptor, serotonin, 5-ht2a [MeSH Descriptor]
OMIM relation
- 5-hydroxytryptamine receptor 2a [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Schizophrenia [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 13: 46368176-46305514 [NCIt concept]
gene_in_chromosomal_location
- 13q14-q21 [NCIt concept]
gene_is_element_in_pathway
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Gap Junction Assembly Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Calcium Signaling [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Muscle Contraction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Steroid Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients