BDNF wt Allele

Preferred Label : BDNF wt Allele;

NCIt synonyms : MGC34632; Brain-Derived Neurotrophic Factor Gene; ANON2; BULN2; Neurotrophin Gene; Brain Derived Neurotrophic Factor wt Allele;

NCIt definition : Human BDNF wild-type allele is located in the vicinity of 11p14.1 and is approximately 67 kb in length. This allele, which encodes brain-derived neurotrophic factor protein, is involved in both stress response regulation and in the survival of striatal neurons. Expression of the allele is decreased in both Alzheimer's and Huntington disease.;

GenBank Accession Number : NM_170735;

Details

Origin ID

C51417;

UMLS CUI

C1705371;

OMIM relation
- Brain-derived neurotrophic factor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 11: 27699851-27633020 [NCIt concept]
gene_in_chromosomal_location
- 11p13 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- WAGRO Syndrome [NCIt concept]
gene_is_element_in_pathway
- Huntington's Disease Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Neurotrophic Factor-Mediated NTRK1 Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Neural Development [NCIt concept]
- Receptor Signaling [NCIt concept]
- Stress Response Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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