FCGR2B wt Allele

Preferred Label : FCGR2B wt Allele;

NCIt synonyms : CD32; FCG2; IGFR2; Fc Fragment of IgG, Low Affinity IIB, Receptor (CD32) Gene; Fc Fragment of IgG, Low Affinity IIB, Receptor for Gene; CD32B; Fc Gamma Receptor IIB wt Allele; RP11-474I16.2; Fc Fragment of IgG, Low Affinity IIB, Receptor for (CD32) Gene;

NCIt definition : Human FCGR2B wild-type allele is located within 1q23 and is approximately 15 kb in length. This allele, which encodes low affinity immunoglobulin gamma Fc region receptor II-b protein, is involved in B-cell activation, host defense responses against foreign pathogens, and immune responses. Chromosomal translocation t(1;22)(q22;q11) leads to FCGR2B hyperexpression in a follicular lymphoma.;

GenBank Accession Number : NM_004001;

Details

Origin ID

C51391;

UMLS CUI

C1705975;

OMIM relation
- Fc fragment of igg receptor iib [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Follicular Lymphoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 1: 158364622-158379489 [NCIt concept]
gene_in_chromosomal_location
- 1q23 [NCIt concept]
gene_is_element_in_pathway
- B Cell Receptor Signaling Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
gene_plays_role_in_process
- B-Cell Activation [NCIt concept]
- Immune Response Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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